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Prilosec (Omeprazole) is a Proton Pump Inhibitor (PPI) used to treat ulcers, heartburn, gastroesophageal reflux, or Zollinger-Ellison syndrome. It works by blocking acid production in the stomach. This medicine may be used in combination with antibiotics (e.g., amoxicillin, clarithromycin) to treat certain types of ulcers. It may also be used to treat other conditions as determined by your doctor.

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Uses

Omeprazole (oh-MEH-pruh-zole) is used to treat various acid-related stomach and/or throat (esophagus) problems (e.g., GERD, ulcers, erosive esophagitis, or Zollinger-Ellison Syndrome). It works by blocking the production of acid in the stomach. When using this medication to treat certain ulcers, it may be prescribed along with certain antibiotics (e.g., amoxicillin, clarithromycin).

How to take

Take this medication by mouth, usually once daily, 15 to 30 minutes before a meal; or as directed by your doctor. The dosage and length of treatment is based on your medical condition and response to therapy. Do not crush or chew the medication. Swallow the medication whole. If you take sucralfate in addition to this medication, take your dose of omeprazole at least 30 minutes before your sucralfate.

Side effects

Headache, diarrhea, gas, or constipation, may occur. If any of these effects persist or worsen, notify your doctor. Tell your doctor immediately if any of these serious side effects occur: rash, stomach/abdominal pain, back pain, unusual tiredness, dizziness, vomiting. Tell your doctor immediately if any of these unlikely but serious side effects occur: chest pain, dark urine, yellowing eyes or skin. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

Precaution

Tell your doctor your medical history, especially of: liver problems, other stomach problems (e.g., tumors), any allergies. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

Drug interactions

Tell your doctor of all prescription and nonprescription medication you may use, especially: diazepam, "blood thinners" (e.g., warfarin), hydantoins (e.g., phenytoin), azole antifungals (e.g., ketoconazole, itraconazole), ampicillin, iron supplements, sucralfate, cilostazol. Do not start or stop any medicine without doctor or pharmacist approval.

Missed dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.